Ivermectin + Praziquantel + Pyrantel Pamoate
1,303 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,303
Total Reports
12
Deaths Reported
90.0%
Death Rate
Active Ingredients
IvermectinPraziquantelPyrantel Pamoate
Administration Routes
OralUnknownIntra-Arterial
Species Affected
Dog 1,146
Unknown 155
Cat 2
Most Affected Breeds
Unknown 158
Retriever - Labrador 156
Shepherd Dog - German 82
Dog (unknown) 80
Pit Bull 66
Retriever - Golden 56
Chihuahua 50
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 36
Terrier - Yorkshire 32
Crossbred Canine/dog 27
Most Reported Reactions
Vomiting 394
Lack of efficacy (endoparasite) - heartworm 393
Diarrhoea 118
Lethargy (see also Central nervous system depression in 'Neurological') 74
Tablets, Abnormal 71
INEFFECTIVE, HOOKS 65
Appearance, Abnormal 63
Containers, Damaged 58
Lack of efficacy (endoparasite) - hookworm 52
Overdose 36
Lack of efficacy (endoparasite) - roundworm NOS 32
Not eating 31
Outcome Breakdown
Outcome Unknown
654 (57.0%)
Recovered/Normal
458 (39.9%)
Ongoing
24 (2.1%)
Died
6 (0.5%)
Euthanized
6 (0.5%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.