Lasix

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93 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
93
Total Reports
28
Deaths Reported
3010.0%
Death Rate

Active Ingredients

Lasix

Administration Routes

UnknownOralIntravenous

Species Affected

Dog 83
Cat 9
Human 1

Most Affected Breeds

Chihuahua 6
Shih Tzu 5
Crossbred Canine/dog 5
Schnauzer - Miniature 4
Dog (unknown) 4
Domestic Shorthair 3
Maltese 3
Retriever - Labrador 3
Domestic Mediumhair 3
Havanese 3

Most Reported Reactions

Death 15
Diarrhoea 13
Death by euthanasia 13
Seizure NOS 12
Vomiting 11
Lethargy (see also Central nervous system depression in Neurological) 9
Lethargy (see also Central nervous system depression in 'Neurological') 8
Abnormal radiograph finding 8
Weakness 8
Cough 7
Not eating 7
Anorexia 7

Outcome Breakdown

Ongoing
33 (35.5%)
Outcome Unknown
18 (19.4%)
Died
15 (16.1%)
Recovered/Normal
14 (15.1%)
Euthanized
13 (14.0%)

Data Summary

Metric Value
Total adverse event reports 93
Reports involving death 28
Case-fatality rate (reported events) 3010.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Lasix Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 93 adverse event reports referencing Lasix, including 28 reports in which the animal died — a 3010.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Lasix. Reported administration routes include Unknown, Oral, Intravenous. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Lasix reports are Dog (83 reports), Cat (9 reports), Human (1 reports), with Dog accounting for the largest share. Within those species, Chihuahua (6), Shih Tzu (5), Crossbred Canine/dog (5) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Lasix are Death (15), Diarrhoea (13), Death by euthanasia (13), Seizure NOS (12). Of the 93 reports with a coded outcome, Ongoing is the leading category at 35.5%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Lasix.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial