Drug profile

The FDA adverse-event record for Terbinafine

82 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Terbinafine. See the species affected, top reactions, and outcomes below.

82
adverse-event reports
8.5%
death-coded share
Dog
most-reported species
15
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
82
Total Reports
7
Deaths Reported
8.5%
Death Rate

Active Ingredients

Terbinafine

Administration Routes

OralUnknownTopical

Species Affected

Dog 68
Cat 14

Most Affected Breeds

Domestic Shorthair 9
Shih Tzu 7
Crossbred Canine/dog 5
Retriever - Labrador 5
Shepherd Dog - German 4
Retriever - Golden 4
Pit Bull 4
Dog (unknown) 4
Terrier - Yorkshire 4
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 3

Most Reported Reactions

Vomiting 15
Lack of efficacy - NOS 12
Diarrhoea 9
Lethargy (see also Central nervous system depression in 'Neurological') 8
Other abnormal test result NOS 8
Not eating 8
Fungal skin infection NOS 8
Weight loss 7
Elevated alanine aminotransferase (ALT) 7
Pruritus 6
Bacterial skin infection NOS 6
Anorexia 5

Outcome Breakdown

Ongoing
28 (34.1%)
Outcome Unknown
25 (30.5%)
Recovered/Normal
20 (24.4%)
Euthanized
6 (7.3%)
Recovered with Sequela
2 (2.4%)
Died
1 (1.2%)

Terbinafine Adverse Event Insights

82 reports name Terbinafine; 7 recorded a death outcome (8.5% of reported events, not a population-level mortality rate). Active ingredient: Terbinafine. Administration routes: Oral, Unknown, Topical.

By species: Dog (68 reports), Cat (14 reports). By breed: Domestic Shorthair (9), Shih Tzu (7), Crossbred Canine/dog (5).

Leading clinical signs: Vomiting (15), Lack of efficacy - NOS (12), Diarrhoea (9), Lethargy (see also Central nervous system depression in 'Neurological') (8). Outcome, 82 coded reports: Ongoing leads at 34.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.