Drug profile

The FDA adverse-event record for Unspecified Fluid Therapy

53 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Fluid Therapy. Species, reactions, and outcomes follow.

#1084 of 2,679
by report volume (all drugs)
53
adverse-event reports
30.2%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Unspecified Fluid Therapy ranks #1077 of 2679 by total reports (53) and #122 of 1130 by death-coded share (30.2%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1077
This drug, reports of 2679
#122
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Unspecified Fluid Therapy has 53 reports now versus 43 in that prior snapshot: 10 more (23.3%).

Report change
+10
Death-coded reports
+1
Death-coded share
−4.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Unspecified Fluid Therapy changes

Signature read: Unspecified Fluid Therapy's 30.2% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
53
Total Reports
16
Deaths Reported
30.2%
Death-coded share of reports

Active Ingredients

Unspecified Fluid Therapy

Administration Routes

SubcutaneousIntravenousUnknown

Species Affected

Dog 39
Cat 14

Most Affected Breeds

Domestic Shorthair 11
Retriever - Golden 4
Bulldog - French 3
Retriever - Labrador 3
Dachshund (unspecified) 2
Pug 2
Terrier - Airedale 2
Domestic Longhair 2
Spaniel (unspecified) 2
Crossbred Canine/dog 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 21
Not eating 17
Diarrhoea 17
Lack of efficacy - NOS 16
Intentional misuse 16
Vomiting 15
Death by euthanasia 12
Abnormal radiograph finding 12
Elevated serum alkaline phosphatase (ALP) 10
Emesis (multiple) 9
Not drinking 8
Not himself/herself 8

Outcome Breakdown

Ongoing
31 (58.5%)
Euthanized
12 (22.6%)
Recovered/Normal
4 (7.5%)
Died
4 (7.5%)
Outcome Unknown
2 (3.8%)

Unspecified Fluid Therapy: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Unspecified Fluid Therapy, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Unspecified Fluid Therapy's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Unspecified Fluid Therapy (#1084 of 2,679 by report volume); death-coded 30.2%. PlainBreed drug row · death-coded share stamp 30.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →