Ivermectin + Pyrantel Pamoate + Praziquantel

305 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

305

Total Reports

Deaths Reported

300.0%

Death Rate

Active Ingredients

Ivermectin + Pyrantel Pamoate + Praziquantel

Administration Routes

OralUnknown

Species Affected

Dog 305

Most Affected Breeds

Retriever - Labrador 52

Terrier - Yorkshire 18

Chihuahua 17

Crossbred Canine/dog 15

Boxer (German Boxer) 13

Beagle 11

Poodle (unspecified) 10

Retriever (unspecified) 9

Terrier (unspecified) 9

Shepherd Dog - German 9

Most Reported Reactions

Emesis 97

Lack of efficacy (endoparasite) - heartworm 55

Vomiting 35

INEFFECTIVE, HEARTWORM LARVAE 32

Lethargy (see also Central nervous system depression in 'Neurological') 30

Lack of efficacy (ectoparasite) - flea 25

Seizure NOS 15

Diarrhoea 14

Lack of efficacy - NOS 13

Emesis (multiple) 13

Other abnormal test result NOS 13

Behavioural disorder NOS 11

Outcome Breakdown

Recovered/Normal

137 (44.9%)

Outcome Unknown

118 (38.7%)

Ongoing

23 (7.5%)

Recovered with Sequela

18 (5.9%)

Died

7 (2.3%)

Euthanized

2 (0.7%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.