Drug profile

The FDA adverse-event record for Imidacolprid And Moxidectin

310 FDA reports name Imidacolprid And Moxidectin, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#412 of 2,679
by report volume (all drugs)
310
adverse-event reports
4.8%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Imidacolprid And Moxidectin ranks #411 of 2679 by total reports (310) and #798 of 1130 by death-coded share (4.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#411
This drug, reports of 2679
#798
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Imidacolprid And Moxidectin has 310 reports now versus 310 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Imidacolprid And Moxidectin changes

Signature read: 310 reports place Imidacolprid And Moxidectin in the upper third of FDA AER volume (#412 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
310
Total Reports
15
Deaths Reported
4.8%
Death-coded share of reports

Active Ingredients

Imidacolprid And Moxidectin

Administration Routes

TopicalUnknownOral

Species Affected

Dog 289
Cat 21

Most Affected Breeds

Retriever - Labrador 72
Shepherd Dog - German 22
Terrier - Bull - American Pit 19
Domestic Shorthair 14
Crossbred Canine/dog 13
Hound (unspecified) 9
Terrier (unspecified) 9
Collie - Border 8
Beagle 8
Mixed (Dog) 6

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 145
INEFFECTIVE, HEARTWORM LARVAE 48
Lack of efficacy - NOS 30
Lethargy (see also Central nervous system depression in 'Neurological') 20
Vomiting 17
Other abnormal test result NOS 15
Anaemia NOS 9
Decreased appetite 9
Lack of efficacy (heartworm) 9
Death 8
Death by euthanasia 8
Seizure NOS 8

Outcome Breakdown

Ongoing
258 (83.2%)
Recovered/Normal
21 (6.8%)
Outcome Unknown
16 (5.2%)
Euthanized
8 (2.6%)
Died
7 (2.3%)

Imidacolprid And Moxidectin: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Imidacolprid And Moxidectin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Imidacolprid And Moxidectin's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Imidacolprid And Moxidectin (#412 of 2,679 by report volume); death-coded 4.8%. PlainBreed drug row · report volume stamp 310 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →