Clodronate Disodium
299 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
299
Total Reports
13
Deaths Reported
430.0%
Death Rate
Active Ingredients
Clodronate Disodium
Administration Routes
IntramuscularUnknownOralAuricular (Otic)
Species Affected
Horse 291
Unknown 5
Human 2
Dog 1
Most Affected Breeds
Quarter Horse 139
Horse (unknown) 35
Thoroughbred 27
Warmblood - Dutch 19
Paint 14
Arab 10
Unknown 7
Oldenburg 6
Warmblood (unspecified) 5
Horse (other) 5
Most Reported Reactions
Elevated creatinine 82
Elevated blood urea nitrogen (BUN) 75
Polyuria 65
Polydipsia 60
Colic 57
Hypercalcaemia 33
Lethargy (see also Central nervous system depression in 'Neurological') 32
Hyperkalaemia 29
Anorexia 25
Pawing 24
Other abnormal test result NOS 21
Hypochloraemia 20
Outcome Breakdown
Recovered/Normal
155 (52.7%)
Outcome Unknown
114 (38.8%)
Euthanized
12 (4.1%)
Ongoing
10 (3.4%)
Recovered with Sequela
2 (0.7%)
Died
1 (0.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.