Dirlotapide

685 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
685
Total Reports
20
Deaths Reported
290.0%
Death Rate

Active Ingredients

Dirlotapide

Administration Routes

OralUnknownTopicalOphthalmic

Species Affected

Dog 602
Unknown 76
Human 7

Most Affected Breeds

Unknown 83
Crossbred Canine/dog 76
Retriever - Labrador 73
Dachshund (unspecified) 43
Retriever - Golden 37
Chihuahua 32
Beagle 31
Dog (unknown) 23
Pug 19
Sheepdog - Shetland 17

Most Reported Reactions

Vomiting 173
Hyperextension 123
INEFFECTIVE, WEIGHT LOSS 123
Anorexia 105
Depression 81
INEFFECTIVE, APPETITE SUPPRESSION 76
Diarrhoea 60
Weight gain 50
Vials, Leaking 49
Elevated alanine aminotransferase (ALT) 37
Elevated serum alkaline phosphatase (SAP) 37
Uncoded sign 28

Outcome Breakdown

Ongoing
66 (55.9%)
Recovered/Normal
20 (16.9%)
Died
19 (16.1%)
Outcome Unknown
12 (10.2%)
Euthanized
1 (0.8%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.