Lotilaner

11,447 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

11,447

Total Reports

295

Deaths Reported

260.0%

Death Rate

Active Ingredients

Lotilaner

Administration Routes

OralUnknownTopicalOtherSubcutaneousOphthalmicCutaneousAuricular (Otic)IntrauterineIntraocular

Species Affected

Dog 9,880

Unknown 778

Cat 762

Human 24

Pig 1

Cattle 1

Goat 1

Most Affected Breeds

Retriever - Labrador 1,192

Unknown 810

Retriever - Golden 729

Dog (unknown) 638

Crossbred Canine/dog 437

Domestic Shorthair 384

Shepherd Dog - Australian 383

Shepherd Dog - German 360

Chihuahua 339

Shih Tzu 296

Most Reported Reactions

Vomiting 2,850

Diarrhoea 1,184

Lack of efficacy (ectoparasite) - tick NOS 811

Other abnormal test result NOS 763

Lethargy (see also Central nervous system depression in 'Neurological') 702

Lack of efficacy (bacteria) - Borrelia 698

UNPALATABLE 681

Seizure NOS 661

Lack of efficacy (ectoparasite) - flea 540

Lack of efficacy (endoparasite) - heartworm 516

Behavioural disorder NOS 492

Not eating 416

Outcome Breakdown

Outcome Unknown

4,784 (44.8%)

Recovered/Normal

3,501 (32.8%)

Ongoing

2,084 (19.5%)

Died

180 (1.7%)

Euthanized

116 (1.1%)

Recovered with Sequela

8 (0.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.