Drug profile

The FDA adverse-event record for Glycopyrrolate

148 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Glycopyrrolate. See the species affected, top reactions, and outcomes below.

148
adverse-event reports
26.4%
death-coded share
Dog
most-reported species
31
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
148
Total Reports
39
Deaths Reported
26.4%
Death Rate

Active Ingredients

Glycopyrrolate

Administration Routes

UnknownSubcutaneousIntramuscularParenteralIntravenousOther

Species Affected

Dog 90
Cat 54
Guinea Pig 3
Rabbit 1

Most Affected Breeds

Domestic Shorthair 32
Retriever - Labrador 17
Domestic Mediumhair 7
Domestic Longhair 7
Crossbred Canine/dog 5
Terrier (unspecified) 4
Maltese 4
Dog (unknown) 4
Shepherd Dog - German 4
Lhasa Apso 3

Most Reported Reactions

Death 31
Cardiac arrest 21
Vomiting 19
Lethargy (see also Central nervous system depression in 'Neurological') 13
Other abnormal test result NOS 13
Not eating 13
Bradycardia 11
Fever 11
Anorexia 10
Inappetence 10
Behavioural disorder NOS 9
Tachycardia 9

Outcome Breakdown

Recovered/Normal
62 (41.9%)
Died
32 (21.6%)
Ongoing
31 (20.9%)
Outcome Unknown
15 (10.1%)
Euthanized
7 (4.7%)
Recovered with Sequela
1 (0.7%)

Glycopyrrolate Adverse Event Insights

148 reports name Glycopyrrolate; 39 recorded a death outcome (26.4% of reported events, not a population-level mortality rate). Active ingredient: Glycopyrrolate. Administration routes: Unknown, Subcutaneous, Intramuscular, Parenteral.

By species: Dog (90 reports), Cat (54 reports), Guinea Pig (3 reports). By breed: Domestic Shorthair (32), Retriever - Labrador (17), Domestic Mediumhair (7).

Leading clinical signs: Death (31), Cardiac arrest (21), Vomiting (19), Lethargy (see also Central nervous system depression in 'Neurological') (13). Outcome, 148 coded reports: Recovered/Normal leads at 41.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.