Drug profile

The FDA adverse-event record for Vitamin B Complex

104 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Vitamin B Complex. See the species affected, top reactions, and outcomes below.

104
adverse-event reports
25.0%
death-coded share
Dog
most-reported species
18
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
104
Total Reports
26
Deaths Reported
25.0%
Death Rate

Active Ingredients

Vitamin B Complex

Administration Routes

UnknownOralParenteralIntravenousSubcutaneousIntramuscular

Species Affected

Dog 57
Cat 34
Cattle 6
Human 5
Horse 2

Most Affected Breeds

Domestic Shorthair 23
Crossbred Canine/dog 6
Pit Bull 6
Unknown 5
Retriever - Labrador 4
Domestic Longhair 3
Cattle (unknown) 3
Siberian Husky 3
Chihuahua 3
Holstein-Friesian also known as Holstein 2

Most Reported Reactions

Vomiting 18
Lethargy (see also Central nervous system depression in 'Neurological') 14
Death 14
Behavioural disorder NOS 14
Other abnormal test result NOS 14
Dehydration 14
Anorexia 12
Not eating 12
Leucocytosis NOS 12
Ataxia 11
Death by euthanasia 11
Diarrhoea 11

Outcome Breakdown

Outcome Unknown
38 (36.5%)
Recovered/Normal
23 (22.1%)
Ongoing
17 (16.3%)
Died
15 (14.4%)
Euthanized
11 (10.6%)

Vitamin B Complex Adverse Event Insights

104 reports name Vitamin B Complex; 26 recorded a death outcome (25.0% of reported events, not a population-level mortality rate). Active ingredient: Vitamin B Complex. Administration routes: Unknown, Oral, Parenteral, Intravenous.

By species: Dog (57 reports), Cat (34 reports), Cattle (6 reports). By breed: Domestic Shorthair (23), Crossbred Canine/dog (6), Pit Bull (6).

Leading clinical signs: Vomiting (18), Lethargy (see also Central nervous system depression in 'Neurological') (14), Death (14), Behavioural disorder NOS (14). Outcome, 104 coded reports: Outcome Unknown leads at 36.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.