Drug profile

The FDA adverse-event record for Glucosamine, Sodium Chondroitin Sulfate, Avocado/Soybean Unsaponifiables

106 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Glucosamine, Sodium Chondroitin Sulfate, Avocado/Soybean Unsaponifiables. See the species affected, top reactions, and outcomes below.

106
adverse-event reports
8.5%
death-coded share
Dog
most-reported species
33
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
106
Total Reports
9
Deaths Reported
8.5%
Death Rate

Active Ingredients

Glucosamine, Sodium Chondroitin Sulfate, Avocado/Soybean Unsaponifiables

Administration Routes

UnknownOralIntramuscular

Species Affected

Dog 101
Cat 5

Most Affected Breeds

Retriever - Labrador 13
Shepherd Dog - German 12
Retriever - Golden 10
Dog (other) 6
Bulldog 4
Domestic Shorthair 4
Chihuahua 4
Dog (unknown) 3
Unknown 3
Collie (unspecified) 2

Most Reported Reactions

Vomiting 33
Not eating 20
Diarrhoea 19
Lethargy (see also Central nervous system depression in Neurological) 16
Lethargy (see also Central nervous system depression in 'Neurological') 8
Lack of efficacy - NOS 7
Panting 7
Incorrect route of drug administration 7
Death by euthanasia 6
Elevated alanine aminotransferase (ALT) 6
Bloody diarrhoea 6
Pain NOS 5

Outcome Breakdown

Recovered/Normal
45 (42.5%)
Outcome Unknown
40 (37.7%)
Ongoing
12 (11.3%)
Euthanized
5 (4.7%)
Died
4 (3.8%)

Glucosamine, Sodium Chondroitin Sulfate, Avocado/Soybean Unsaponifiables Adverse Event Insights

106 reports name Glucosamine, Sodium Chondroitin Sulfate, Avocado/Soybean Unsaponifiables; 9 recorded a death outcome (8.5% of reported events, not a population-level mortality rate). Active ingredient: Glucosamine, Sodium Chondroitin Sulfate, Avocado/Soybean Unsaponifiables. Administration routes: Unknown, Oral, Intramuscular.

By species: Dog (101 reports), Cat (5 reports). By breed: Retriever - Labrador (13), Shepherd Dog - German (12), Retriever - Golden (10).

Leading clinical signs: Vomiting (33), Not eating (20), Diarrhoea (19), Lethargy (see also Central nervous system depression in Neurological) (16). Outcome, 106 coded reports: Recovered/Normal leads at 42.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.