Phenobarbital
1,560 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,560
Total Reports
192
Deaths Reported
1230.0%
Death Rate
Active Ingredients
Phenobarbital
Administration Routes
OralUnknownIntravenousRectalSubcutaneousOtherParenteral
Species Affected
Dog 1,442
Cat 113
Unknown 4
Other Canids 1
Most Affected Breeds
Retriever - Labrador 127
Chihuahua 87
Domestic Shorthair 63
Retriever - Golden 62
Crossbred Canine/dog 58
Shepherd Dog - German 50
Dog (unknown) 48
Terrier - Yorkshire 46
Shepherd Dog - Australian 45
Beagle 42
Most Reported Reactions
Seizure NOS 593
Lethargy (see also Central nervous system depression in 'Neurological') 183
Vomiting 155
Death by euthanasia 114
Other abnormal test result NOS 105
Emesis 93
Lack of efficacy - NOS 93
Ataxia 90
Diarrhoea 84
Death 76
Behavioural disorder NOS 74
Anorexia 74
Outcome Breakdown
Recovered/Normal
475 (30.7%)
Ongoing
455 (29.4%)
Outcome Unknown
364 (23.5%)
Euthanized
109 (7.0%)
Died
83 (5.4%)
Recovered with Sequela
63 (4.1%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.