Drug profile

The FDA adverse-event record for Imrab 1 Tf - 1905.27

98 FDA reports name Imrab 1 Tf - 1905.27, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#786 of 2,679
by report volume (all drugs)
98
adverse-event reports
12.2%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Imrab 1 Tf - 1905.27 ranks #784 of 2679 by total reports (98) and #450 of 1130 by death-coded share (12.2%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#784
This drug, reports of 2679
#450
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Imrab 1 Tf - 1905.27 has 98 reports now versus 96 in that prior snapshot: 2 more (2.1%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Imrab 1 Tf - 1905.27 changes

Signature read: 98 reports place Imrab 1 Tf - 1905.27 in the upper third of FDA AER volume (#786 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
98
Total Reports
12
Deaths Reported
12.2%
Death-coded share of reports

Active Ingredients

Imrab 1 Tf - 1905.27

Administration Routes

SubcutaneousUnknown

Species Affected

Dog 82
Cat 16

Most Affected Breeds

Domestic Shorthair 13
Shih Tzu 12
Chihuahua 9
Terrier - Yorkshire 7
Poodle - Toy 4
Pit Bull 4
Retriever - Labrador 4
Bulldog - French 3
Spitz - German Pomeranian 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 3

Most Reported Reactions

Vomiting 42
Diarrhoea 16
Lethargy (see also Central nervous system depression in Neurological) 14
Lethargy (see also Central nervous system depression in 'Neurological') 13
Anorexia 10
Fever 10
Leucocytosis NOS 10
Neutrophilia 9
Not eating 9
Injection site lump 8
Other abnormal test result NOS 8
Death 7

Outcome Breakdown

Outcome Unknown
44 (44.9%)
Recovered/Normal
30 (30.6%)
Ongoing
12 (12.2%)
Died
7 (7.1%)
Euthanized
5 (5.1%)

Imrab 1 Tf - 1905.27: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Imrab 1 Tf - 1905.27, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Imrab 1 Tf - 1905.27 (#786 of 2,679 by report volume); death-coded 12.2%. PlainBreed drug row · report volume stamp 98 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →