Fipronil/S-Methoprene
101 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
101
Total Reports
12
Deaths Reported
1190.0%
Death Rate
Active Ingredients
Fipronil/S-Methoprene
Administration Routes
TopicalUnknownOral
Species Affected
Dog 87
Cat 14
Most Affected Breeds
Retriever - Labrador 15
Domestic Shorthair 10
Terrier - West Highland White 7
Spaniel - King Charles Cavalier 6
Chihuahua 5
Shih Tzu 5
Shepherd Dog - German 3
Shepherd Dog - Australian 3
Collie (unspecified) 2
Spaniel - Cocker American 2
Most Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 24
Other abnormal test result NOS 14
Vomiting 12
Diarrhoea 11
Panting 8
Seizure NOS 8
Pruritus 8
Lack of efficacy (ectoparasite) - flea 8
Decreased appetite 8
Emesis 7
Anorexia 7
Abnormal radiograph finding 7
Outcome Breakdown
Recovered/Normal
44 (43.6%)
Ongoing
28 (27.7%)
Outcome Unknown
16 (15.8%)
Euthanized
6 (5.9%)
Died
6 (5.9%)
Recovered with Sequela
1 (1.0%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.