Drug profile

The FDA adverse-event record for Lasalocid

101 FDA reports name Lasalocid, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#774 of 2,679
by report volume (all drugs)
101
adverse-event reports
51.5%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Lasalocid ranks #772 of 2679 by total reports (101) and #57 of 1130 by death-coded share (51.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#772
This drug, reports of 2679
#57
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lasalocid has 101 reports now versus 101 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lasalocid changes

Signature read: Lasalocid's 51.5% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
101
Total Reports
52
Deaths Reported
51.5%
Death-coded share of reports

Active Ingredients

Lasalocid

Administration Routes

OralUnknown

Species Affected

Cattle 60
Unknown 25
Horse 4
Sheep 4
Pig 2
Goat 2
Turkey 1
Other 1
Dog 1
Chicken 1

Most Affected Breeds

Holstein-Friesian also known as Holstein 27
Unknown 26
Cattle (unknown) 16
Crossbred Bovine/Cattle 6
Sheep (unknown) 4
Mixed (Cattle) 4
Horse (other) 2
Jersey 2
Turkey (unknown) 1
Pig (unknown) 1

Most Reported Reactions

Death 48
Potency, Low 9
Accidental exposure 8
Recumbency 7
Lot # and /or Expiration date missing 7
Lack of efficacy (protozoa) - Coccidia 6
Diarrhoea 6
Lack of efficacy - NOS 6
Inappropriate preparation of medication 4
Anorexia 4
Product Defect, General 4
Pulmonary oedema 4

Outcome Breakdown

Died
52 (67.5%)
Outcome Unknown
14 (18.2%)
Ongoing
6 (7.8%)
Recovered/Normal
4 (5.2%)
Recovered with Sequela
1 (1.3%)

Lasalocid: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Lasalocid, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (101 here).

Similar death-coded share

Nearest other drugs by death-coded share (51.5% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lasalocid (#774 of 2,679 by report volume); death-coded 51.5%. PlainBreed drug row · death-coded share stamp 51.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →