Fipronil, S-Methoprene
140 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
140
Total Reports
2
Deaths Reported
140.0%
Death Rate
Active Ingredients
Fipronil, S-Methoprene
Administration Routes
TopicalUnknownOralCutaneousOther
Species Affected
Dog 81
Cat 57
Other 2
Most Affected Breeds
Domestic Shorthair 33
Retriever - Labrador 9
Shih Tzu 8
Domestic Mediumhair 6
Pug 4
Terrier - Yorkshire 4
Shepherd Dog - German 4
Domestic Longhair 4
Cat (unknown) 4
Pit Bull 3
Most Reported Reactions
Lack of efficacy (ectoparasite) - flea 69
Lethargy (see also Central nervous system depression in 'Neurological') 17
Diarrhoea 17
Scratching 15
Vomiting 12
Lack of efficacy - NOS 8
Panting 7
Drooling 6
Emesis 6
Anorexia 6
Licking 4
Hyperactivity 4
Outcome Breakdown
Outcome Unknown
85 (60.7%)
Recovered/Normal
35 (25.0%)
Ongoing
18 (12.9%)
Died
2 (1.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.