Drug profile

The FDA adverse-event record for Flumethrin-Imidacloprid Collar

51 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Flumethrin-Imidacloprid Collar. See the species affected, top reactions, and outcomes below.

51
adverse-event reports
2.0%
death-coded share
Dog
most-reported species
41
Lack of efficacy (ectoparasite) - flea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
51
Total Reports
1
Deaths Reported
2.0%
Death Rate

Active Ingredients

Flumethrin-Imidacloprid Collar

Administration Routes

TopicalOral

Species Affected

Dog 34
Cat 17

Most Affected Breeds

Domestic Shorthair 7
Domestic Mediumhair 4
Retriever - Golden 3
Dog (unknown) 3
Cat (unknown) 3
Shepherd Dog - German 3
Dachshund (unspecified) 2
Retriever - Labrador 2
Chihuahua 2
Shih Tzu 2

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 41
Scratching 3
Panting 2
Vomiting 2
Sleepiness - systemic disorder 2
Lack of efficacy - NOS 2
Hyperactivity 1
Biting - pruritus (see also 'Behavioural disorders') 1
Licking 1
Twitching 1
Skin disorders NOS 1
Lack of efficacy (ectoparasite) - tick NOS 1

Outcome Breakdown

Outcome Unknown
46 (90.2%)
Recovered/Normal
3 (5.9%)
Died
1 (2.0%)
Ongoing
1 (2.0%)

Flumethrin-Imidacloprid Collar Adverse Event Insights

51 reports name Flumethrin-Imidacloprid Collar; 1 recorded a death outcome (2.0% of reported events, not a population-level mortality rate). Active ingredient: Flumethrin-Imidacloprid Collar. Administration routes: Topical, Oral.

By species: Dog (34 reports), Cat (17 reports). By breed: Domestic Shorthair (7), Domestic Mediumhair (4), Retriever - Golden (3).

Leading clinical signs: Lack of efficacy (ectoparasite) - flea (41), Scratching (3), Panting (2), Vomiting (2). Outcome, 51 coded reports: Outcome Unknown leads at 90.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.