Drug profile

The FDA adverse-event record for Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine, Killed Virus

68 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine, Killed Virus. See the species affected, top reactions, and outcomes below.

68
adverse-event reports
10.3%
death-coded share
Cat
most-reported species
23
Fever - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
68
Total Reports
7
Deaths Reported
10.3%
Death Rate

Active Ingredients

Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine, Killed Virus

Administration Routes

SubcutaneousParenteralUnknown

Species Affected

Cat 68

Most Affected Breeds

Domestic Shorthair 51
Domestic Longhair 5
Domestic Mediumhair 4
Cat (unknown) 3
Maine Coon 2
Siamese 1
Cat (other) 1
Russian 1

Most Reported Reactions

Fever 23
Lethargy (see also Central nervous system depression in 'Neurological') 22
Not eating 20
Lethargy (see also Central nervous system depression in Neurological) 10
Vomiting 9
Injection site pain 8
Behavioural disorder NOS 8
Anorexia 7
Elevated temperature 6
Hiding 6
Pain NOS 6
Injection site swelling 5

Outcome Breakdown

Recovered/Normal
33 (48.5%)
Ongoing
16 (23.5%)
Outcome Unknown
12 (17.6%)
Died
4 (5.9%)
Euthanized
3 (4.4%)

Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine, Killed Virus Adverse Event Insights

68 reports name Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine, Killed Virus; 7 recorded a death outcome (10.3% of reported events, not a population-level mortality rate). Active ingredient: Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine, Killed Virus. Administration routes: Subcutaneous, Parenteral, Unknown.

By species: Cat (68 reports). By breed: Domestic Shorthair (51), Domestic Longhair (5), Domestic Mediumhair (4).

Leading clinical signs: Fever (23), Lethargy (see also Central nervous system depression in 'Neurological') (22), Not eating (20), Lethargy (see also Central nervous system depression in Neurological) (10). Outcome, 68 coded reports: Recovered/Normal leads at 48.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.