Buprenorphine Hcl
258 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
258
Total Reports
83
Deaths Reported
3220.0%
Death Rate
Active Ingredients
Buprenorphine Hcl
Administration Routes
UnknownIntramuscularSubcutaneousIntravenousOral
Species Affected
Dog 141
Cat 115
Guinea Pig 1
Rabbit 1
Most Affected Breeds
Domestic Shorthair 75
Retriever - Labrador 14
Domestic Longhair 14
Dog (unknown) 10
Cat (unknown) 7
Schnauzer - Miniature 7
Chihuahua 6
Domestic Mediumhair 6
Terrier - Bull - American Pit 6
Shih Tzu 5
Most Reported Reactions
Vomiting 47
Lethargy (see also Central nervous system depression in 'Neurological') 47
Other abnormal test result NOS 46
Death by euthanasia 45
Anorexia 38
Death 37
Elevated alanine aminotransferase (ALT) 26
Fever 25
Elevated serum alkaline phosphatase (SAP) 24
Emesis 23
Abnormal radiograph finding 22
Diarrhoea 22
Outcome Breakdown
Ongoing
98 (37.8%)
Recovered/Normal
62 (23.9%)
Euthanized
44 (17.0%)
Died
39 (15.1%)
Outcome Unknown
15 (5.8%)
Recovered with Sequela
1 (0.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.