Sevoflurane
841 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
841
Total Reports
165
Deaths Reported
1960.0%
Death Rate
Active Ingredients
Sevoflurane
Administration Routes
Respiratory (Inhalation)UnknownNasalOtherIntravenousSubcutaneousEndotrachealTransdermal
Species Affected
Dog 497
Cat 273
Unknown 20
Human 14
Horse 11
Rabbit 5
Guinea Pig 4
Other 3
Ferret 3
Monkey 2
Most Affected Breeds
Domestic Shorthair 130
Unknown 61
Dog (unknown) 56
Retriever - Labrador 40
Cat (unknown) 35
Crossbred Canine/dog 28
Domestic Longhair 24
Chihuahua 22
Domestic (unspecified) 19
Terrier - Yorkshire 19
Most Reported Reactions
Death 120
Vomiting 99
Lethargy (see also Central nervous system depression in 'Neurological') 88
Anorexia 75
Bradycardia 70
Cardiac arrest 64
Not eating 48
Diarrhoea 47
INEFFECTIVE, ANESTHESIA 45
Behavioural disorder NOS 43
Other abnormal test result NOS 40
Hypothermia 40
Outcome Breakdown
Recovered/Normal
261 (36.4%)
Ongoing
195 (27.2%)
Died
129 (18.0%)
Outcome Unknown
94 (13.1%)
Euthanized
36 (5.0%)
Recovered with Sequela
3 (0.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.