Drug profile

The FDA adverse-event record for Carporfen

53 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Carporfen. Species, reactions, and outcomes follow.

#1077 of 2,679
by report volume (all drugs)
53
adverse-event reports
17.0%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Carporfen ranks #1077 of 2679 by total reports (53) and #305 of 1130 by death-coded share (17.0%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1077
This drug, reports of 2679
#305
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Carporfen has 53 reports now versus 51 in that prior snapshot: 2 more (3.9%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Carporfen changes

Signature read: Carporfen's 17.0% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
53
Total Reports
9
Deaths Reported
17.0%
Death-coded share of reports

Active Ingredients

Carporfen

Administration Routes

UnknownOral

Species Affected

Dog 53

Most Affected Breeds

Retriever - Labrador 15
Shepherd Dog - German 6
Shepherd Dog - Australian 4
Boxer (German Boxer) 3
Crossbred Canine/dog 3
Retriever - Golden 3
Chihuahua 2
Cattle Dog (unspecified) 2
Shih Tzu 1
Retriever (unspecified) 1

Most Reported Reactions

Polydipsia 8
Polyuria 7
Death by euthanasia 6
Paraparesis 6
Panting 5
Vomiting 5
Elevated alanine aminotransferase (ALT) 5
Abnormal radiograph finding 4
Diarrhoea 4
Loose stool 3
Difficulty standing 3
Restlessness 3

Outcome Breakdown

Ongoing
21 (39.6%)
Outcome Unknown
12 (22.6%)
Recovered/Normal
11 (20.8%)
Euthanized
6 (11.3%)
Died
3 (5.7%)

Carporfen: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Carporfen, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Carporfen (#1077 of 2,679 by report volume); death-coded 17.0%. PlainBreed drug row · death-coded share stamp 17.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →