Drug profile

The FDA adverse-event record for Levamisole Hydrochloride;Doramectin

111 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Levamisole Hydrochloride;Doramectin. See the species affected, top reactions, and outcomes below.

111
adverse-event reports
18.9%
death-coded share
Cattle
most-reported species
18
Injection site swelling - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
111
Total Reports
21
Deaths Reported
18.9%
Death Rate

Active Ingredients

Levamisole Hydrochloride;Doramectin

Administration Routes

SubcutaneousUnknownRespiratory (Inhalation)Topical

Species Affected

Cattle 59
Unknown 42
Human 7
Goat 2
Pig 1

Most Affected Breeds

Unknown 49
Mixed (Cattle) 46
Aberdeen Angus 7
Goat (unknown) 2
Hereford cattle 2
Red Angus 1
Pig (unknown) 1
Charolais 1
Brangus 1
Holstein-Friesian also known as Holstein 1

Most Reported Reactions

Injection site swelling 18
Death 17
Closure, Abnormal 12
Containers, Damaged 11
Lack of efficacy - NOS 9
Closure, Missing 8
Inappropriate packaging or design 8
Injection site abscess 6
Necropsy performed 5
Containers, Abnormal 5
Containers, Leaking 4
Intentional misuse 4

Outcome Breakdown

Outcome Unknown
39 (50.0%)
Died
20 (25.6%)
Recovered/Normal
10 (12.8%)
Ongoing
8 (10.3%)
Euthanized
1 (1.3%)

Levamisole Hydrochloride;Doramectin Adverse Event Insights

111 reports name Levamisole Hydrochloride;Doramectin; 21 recorded a death outcome (18.9% of reported events, not a population-level mortality rate). Active ingredient: Levamisole Hydrochloride;Doramectin. Administration routes: Subcutaneous, Unknown, Respiratory (Inhalation), Topical.

By species: Cattle (59 reports), Unknown (42 reports), Human (7 reports). By breed: Unknown (49), Mixed (Cattle) (46), Aberdeen Angus (7).

Leading clinical signs: Injection site swelling (18), Death (17), Closure, Abnormal (12), Containers, Damaged (11). Outcome, 78 coded reports: Outcome Unknown leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.