Drug profile

The FDA adverse-event record for Thiabendazole, Dexamethasone, Neomycin Sulfate

156 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Thiabendazole, Dexamethasone, Neomycin Sulfate. See the species affected, top reactions, and outcomes below.

156
adverse-event reports
17.9%
death-coded share
Cat
most-reported species
42
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
156
Total Reports
28
Deaths Reported
17.9%
Death Rate

Active Ingredients

Thiabendazole, Dexamethasone, Neomycin Sulfate

Administration Routes

Auricular (Otic)TopicalUnknownOphthalmicOther

Species Affected

Cat 96
Dog 60

Most Affected Breeds

Domestic Shorthair 52
Domestic Longhair 9
Domestic Mediumhair 8
Retriever - Labrador 8
Cat (other) 8
Shih Tzu 6
Cat (unknown) 4
Terrier - Yorkshire 3
Persian 3
Maltese 3

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 42
Other abnormal test result NOS 20
Vomiting 19
Anorexia 15
Death 15
Decreased appetite 14
Seizure NOS 13
Diarrhoea 12
Death by euthanasia 11
Weight loss 11
Elevated alanine aminotransferase (ALT) 11
Fever 10

Outcome Breakdown

Ongoing
96 (61.5%)
Outcome Unknown
21 (13.5%)
Died
17 (10.9%)
Euthanized
11 (7.1%)
Recovered/Normal
11 (7.1%)

Thiabendazole, Dexamethasone, Neomycin Sulfate Adverse Event Insights

156 reports name Thiabendazole, Dexamethasone, Neomycin Sulfate; 28 recorded a death outcome (17.9% of reported events, not a population-level mortality rate). Active ingredient: Thiabendazole, Dexamethasone, Neomycin Sulfate. Administration routes: Auricular (Otic), Topical, Unknown, Ophthalmic.

By species: Cat (96 reports), Dog (60 reports). By breed: Domestic Shorthair (52), Domestic Longhair (9), Domestic Mediumhair (8).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (42), Other abnormal test result NOS (20), Vomiting (19), Anorexia (15). Outcome, 156 coded reports: Ongoing leads at 61.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.