Enrofloxacin + Ketoconazole + Triamcinolone

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49 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
49
Total Reports
3
Deaths Reported
610.0%
Death Rate

Active Ingredients

EnrofloxacinEnrofloxacin + Ketoconazole + TriamcinoloneKetoconazoleTriamcinolone

Administration Routes

Auricular (Otic)UnknownTopical

Species Affected

Dog 47
Cat 2

Most Affected Breeds

Pit Bull 7
Shepherd Dog - German 5
Terrier - Yorkshire 3
Unknown 3
Schnauzer - Miniature 2
Dog (unknown) 2
Retriever - Labrador 2
Pointing Dog - Hungarian Short-haired (Vizsla) 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Domestic Shorthair 2

Most Reported Reactions

Deafness 13
Lack of efficacy - NOS 5
Loss of hearing 5
Vomiting 4
Partial deafness 4
Temporary deafness 3
Ear pain 2
Vocalisation 2
Application site pain 2
Nystagmus 2
Death 2
Panting 2

Outcome Breakdown

Outcome Unknown
20 (48.8%)
Recovered with Sequela
7 (17.1%)
Ongoing
6 (14.6%)
Recovered/Normal
5 (12.2%)
Died
3 (7.3%)

Data Summary

Metric Value
Total adverse event reports 49
Reports involving death 3
Case-fatality rate (reported events) 610.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 4

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Enrofloxacin + Ketoconazole + Triamcinolone Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 49 adverse event reports referencing Enrofloxacin + Ketoconazole + Triamcinolone, including 3 reports in which the animal died — a 610.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredients on file: Enrofloxacin, Enrofloxacin + Ketoconazole + Triamcinolone, Ketoconazole, Triamcinolone. Reported administration routes include Auricular (Otic), Unknown, Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Enrofloxacin + Ketoconazole + Triamcinolone reports are Dog (47 reports), Cat (2 reports), with Dog accounting for the largest share. Within those species, Pit Bull (7), Shepherd Dog - German (5), Terrier - Yorkshire (3) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Enrofloxacin + Ketoconazole + Triamcinolone are Deafness (13), Lack of efficacy - NOS (5), Loss of hearing (5), Vomiting (4). Of the 41 reports with a coded outcome, Outcome Unknown is the leading category at 48.8%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Enrofloxacin + Ketoconazole + Triamcinolone.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial