Drug profile

The FDA adverse-event record for Bexagliflozin

3,249 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bexagliflozin. See the species affected, top reactions, and outcomes below.

3,249
adverse-event reports
8.2%
death-coded share
Cat
most-reported species
1,429
Ketosis - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,249
Total Reports
266
Deaths Reported
8.2%
Death Rate

Active Ingredients

Bexagliflozin

Administration Routes

OralUnknownTopicalIntrathoracicTransdermalSubcutaneousOther

Species Affected

Cat 3,196
Unknown 37
Dog 14
Fallow 1
Other 1

Most Affected Breeds

Domestic Shorthair 2,017
Cat (unknown) 508
Domestic Longhair 258
Domestic Mediumhair 166
Siamese 60
Maine Coon 50
Unknown 39
Domestic (unspecified) 15
American Shorthair 14
Russian 13

Most Reported Reactions

Ketosis 1,429
Weight loss 836
Hyperglycaemia 726
Diarrhoea 616
Lack of efficacy - NOS 432
Lethargy (see also Central nervous system depression in Neurological) 373
Vomiting 370
Other abnormal test result NOS 353
Hypoglycaemia 347
Not eating 285
Glucosuria 278
Diabetic ketoacidosis 240

Outcome Breakdown

Outcome Unknown
1,397 (43.4%)
Ongoing
1,302 (40.5%)
Recovered/Normal
253 (7.9%)
Euthanized
208 (6.5%)
Died
58 (1.8%)

Bexagliflozin Adverse Event Insights

3,249 reports name Bexagliflozin; 266 recorded a death outcome (8.2% of reported events, not a population-level mortality rate). Active ingredient: Bexagliflozin. Administration routes: Oral, Unknown, Topical, Intrathoracic.

By species: Cat (3,196 reports), Unknown (37 reports), Dog (14 reports). By breed: Domestic Shorthair (2,017), Cat (unknown) (508), Domestic Longhair (258).

Leading clinical signs: Ketosis (1,429), Weight loss (836), Hyperglycaemia (726), Diarrhoea (616). Outcome, 3,218 coded reports: Outcome Unknown leads at 43.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.