Drug profile

The FDA adverse-event record for Bexagliflozin

3,835 FDA reports name Bexagliflozin, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#58 of 2,679
by report volume (all drugs)
3,835
adverse-event reports
8.0%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Bexagliflozin ranks #58 of 2679 by total reports (3,835) and #640 of 1130 by death-coded share (8.0%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#58
This drug, reports of 2679
#640
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bexagliflozin has 3,835 reports now versus 3,578 in that prior snapshot: 257 more (7.2%).

Report change
+257
Death-coded reports
+11
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bexagliflozin changes

Signature read: 3,835 reports place Bexagliflozin in the upper third of FDA AER volume (#58 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,835
Total Reports
306
Deaths Reported
8.0%
Death-coded share of reports

Active Ingredients

Bexagliflozin

Administration Routes

OralUnknownTopicalIntrathoracicSubcutaneousTransdermalOther

Species Affected

Cat 3,770
Unknown 45
Dog 18
Other 1
Fallow 1

Most Affected Breeds

Domestic Shorthair 2,384
Cat (unknown) 590
Domestic Longhair 307
Domestic Mediumhair 199
Siamese 76
Maine Coon 57
Unknown 47
American Shorthair 16
Domestic (unspecified) 15
Russian 13

Most Reported Reactions

Ketosis 1,470
Weight loss 1,020
Hyperglycaemia 849
Diarrhoea 723
Lack of efficacy - NOS 552
Vomiting 429
Lethargy (see also Central nervous system depression in Neurological) 422
Hypoglycaemia 403
Other abnormal test result NOS 389
Glucosuria 355
Not eating 332
Diabetic ketoacidosis 268

Outcome Breakdown

Outcome Unknown
1,611 (42.4%)
Ongoing
1,590 (41.9%)
Recovered/Normal
291 (7.7%)
Euthanized
241 (6.3%)
Died
65 (1.7%)

Bexagliflozin: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Bexagliflozin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bexagliflozin (#58 of 2,679 by report volume); death-coded 8.0%. PlainBreed drug row · report volume stamp 3,835 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →