Milbemycin/Lufenuron Tablets
3,628 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,628
Total Reports
53
Deaths Reported
150.0%
Death Rate
Active Ingredients
Milbemycin/Lufenuron Tablets
Administration Routes
OralUnknownTopicalIontophoresis
Species Affected
Dog 3,501
Unknown 120
Human 7
Most Affected Breeds
Crossbred Canine/dog 987
Retriever - Labrador 380
Retriever - Golden 159
Shepherd Dog - German 151
Unknown 129
Dog (unknown) 97
Pit Bull 93
Shepherd Dog - Australian 88
Beagle 79
Terrier (unspecified) 62
Most Reported Reactions
Lack of efficacy (endoparasite) - heartworm 1,386
Lack of efficacy (endoparasite) - hookworm 552
Vomiting 310
Lack of efficacy (endoparasite) - roundworm NOS 301
Lack of efficacy (ectoparasite) - flea 204
Emesis (multiple) 131
Diarrhoea 124
Lethargy (see also Central nervous system depression in 'Neurological') 112
Drug dose omission 101
Lack of efficacy (endoparasite) - whipworm 95
INEFFECTIVE, HOOKS 84
Underfilling, Package 80
Outcome Breakdown
Ongoing
2,673 (76.2%)
Recovered/Normal
679 (19.3%)
Outcome Unknown
78 (2.2%)
Euthanized
30 (0.9%)
Recovered with Sequela
26 (0.7%)
Died
24 (0.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.