Butorphanol
3,616 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,616
Total Reports
647
Deaths Reported
1790.0%
Death Rate
Active Ingredients
Butorphanol
Administration Routes
UnknownIntramuscularIntravenousParenteralSubcutaneousOralOtherIntra-ArterialSubmucosalOphthalmic
Species Affected
Dog 2,322
Cat 1,184
Horse 88
Unknown 5
Other 3
Other Equids 3
Parrot 2
Other Mammals 1
Other Birds 1
Primate 1
Most Affected Breeds
Domestic Shorthair 638
Retriever - Labrador 267
Dog (unknown) 247
Cat (unknown) 126
Domestic Longhair 111
Shepherd Dog - German 91
Chihuahua 91
Terrier - Bull - American Pit 88
Retriever - Golden 72
Domestic Mediumhair 70
Most Reported Reactions
Lack of efficacy - NOS 479
Death 388
Vomiting 368
Lethargy (see also Central nervous system depression in 'Neurological') 296
Anorexia 241
Diarrhoea 241
Bradycardia 233
Not eating 202
Death by euthanasia 199
Lethargy (see also Central nervous system depression in Neurological) 196
Seizure NOS 188
Behavioural disorder NOS 184
Outcome Breakdown
Recovered/Normal
1,447 (39.8%)
Ongoing
942 (25.9%)
Outcome Unknown
585 (16.1%)
Died
430 (11.8%)
Euthanized
217 (6.0%)
Recovered with Sequela
13 (0.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.