Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate)

3,601 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

3,601

Total Reports

201

Deaths Reported

560.0%

Death Rate

Active Ingredients

Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate)

Administration Routes

UnknownOralSubcutaneousTopicalOtherOphthalmicRespiratory (Inhalation)

Species Affected

Unknown 2,290

Dog 921

Cat 380

Human 6

Ferret 3

Parrot 1

Most Affected Breeds

Unknown 2,299

Domestic Shorthair 229

Retriever - Labrador 87

Cat (other) 66

Chihuahua 59

Dog (unknown) 44

Shih Tzu 44

Terrier - Bull - American Pit 40

Terrier - Yorkshire 33

Bulldog - French 32

Most Reported Reactions

Color, Abnormal 2,096

Suspension, Abnormal 535

Closure, Abnormal 288

Vomiting 287

Lack of efficacy - NOS 198

Lethargy (see also Central nervous system depression in 'Neurological') 161

Granules/Powder, Abnormal 136

Diarrhoea 125

Not eating 114

Seal, Abnormal 108

Lethargy (see also Central nervous system depression in Neurological) 104

Death by euthanasia 103

Outcome Breakdown

Ongoing

654 (49.7%)

Outcome Unknown

275 (20.9%)

Recovered/Normal

182 (13.8%)

Euthanized

104 (7.9%)

Died

100 (7.6%)

Recovered with Sequela

1 (0.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.