Drug profile

The FDA adverse-event record for Adequan

428 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Adequan. See the species affected, top reactions, and outcomes below.

428
adverse-event reports
13.1%
death-coded share
Dog
most-reported species
57
Ataxia - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
428
Total Reports
56
Deaths Reported
13.1%
Death Rate

Active Ingredients

Adequan

Administration Routes

UnknownSubcutaneousIntramuscularOralIntravenousParenteral

Species Affected

Dog 372
Cat 54
Horse 2

Most Affected Breeds

Retriever - Labrador 71
Shepherd Dog - German 31
Domestic Shorthair 28
Retriever - Golden 25
Terrier - Bull - American Pit 19
Collie - Border 15
Crossbred Canine/dog 14
Dog (unknown) 10
Chihuahua 9
Terrier (unspecified) 9

Most Reported Reactions

Ataxia 57
Lethargy (see also Central nervous system depression in Neurological) 54
Death by euthanasia 42
Polydipsia 40
Polyuria 39
Urinary incontinence 36
Vomiting 35
Diarrhoea 31
Urinary tract infection 31
Limb weakness 31
Lack of efficacy - NOS 30
Not eating 26

Outcome Breakdown

Ongoing
270 (63.1%)
Recovered/Normal
57 (13.3%)
Outcome Unknown
45 (10.5%)
Euthanized
42 (9.8%)
Died
14 (3.3%)

Adequan Adverse Event Insights

428 reports name Adequan; 56 recorded a death outcome (13.1% of reported events, not a population-level mortality rate). Active ingredient: Adequan. Administration routes: Unknown, Subcutaneous, Intramuscular, Oral.

By species: Dog (372 reports), Cat (54 reports), Horse (2 reports). By breed: Retriever - Labrador (71), Shepherd Dog - German (31), Domestic Shorthair (28).

Leading clinical signs: Ataxia (57), Lethargy (see also Central nervous system depression in Neurological) (54), Death by euthanasia (42), Polydipsia (40). Outcome, 428 coded reports: Ongoing leads at 63.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.