Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St
1,300 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,300
Total Reports
169
Deaths Reported
1300.0%
Death Rate
Active Ingredients
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St
Administration Routes
SubcutaneousUnknownSubconjunctivalIntramuscular
Species Affected
Dog 1,299
Cat 1
Most Affected Breeds
Retriever - Labrador 109
Terrier - Bull - American Pit 90
Chihuahua 73
Terrier - Yorkshire 68
Shih Tzu 54
Boxer (German Boxer) 54
Pug 47
Retriever - Golden 44
Dachshund (unspecified) 38
Shepherd Dog - German 33
Most Reported Reactions
Vomiting 449
Lethargy (see also Central nervous system depression in 'Neurological') 360
Facial swelling (see also 'Skin') 245
Anaphylactoid reaction 181
Diarrhoea 174
Other abnormal test result NOS 153
Anorexia 134
Pale mucous membrane 130
Hives (see also 'Skin') 121
Emesis 113
Anaphylaxis 110
Urticaria 106
Outcome Breakdown
Ongoing
600 (46.0%)
Recovered/Normal
483 (37.1%)
Died
93 (7.1%)
Euthanized
76 (5.8%)
Outcome Unknown
50 (3.8%)
Recovered with Sequela
1 (0.1%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.