Alprazolam
418 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
418
Total Reports
33
Deaths Reported
790.0%
Death Rate
Active Ingredients
Alprazolam
Administration Routes
OralUnknownIntramuscular
Species Affected
Dog 382
Human 19
Cat 16
Unknown 1
Most Affected Breeds
Retriever - Labrador 51
Crossbred Canine/dog 23
Chihuahua 23
Unknown 20
Shih Tzu 16
Terrier - Yorkshire 12
Shepherd Dog - German 12
Retriever - Golden 9
Domestic Shorthair 9
Terrier (unspecified) 9
Most Reported Reactions
Vomiting 72
Lethargy (see also Central nervous system depression in 'Neurological') 53
Emesis 47
Lack of efficacy - NOS 43
Anxiety 36
Diarrhoea 34
Seizure NOS 30
Other abnormal test result NOS 25
Elevated alanine aminotransferase (ALT) 24
Death by euthanasia 24
Anorexia 21
Elevated serum alkaline phosphatase (SAP) 20
Outcome Breakdown
Recovered/Normal
142 (34.1%)
Outcome Unknown
115 (27.6%)
Ongoing
112 (26.9%)
Euthanized
23 (5.5%)
Recovered with Sequela
14 (3.4%)
Died
10 (2.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.