Thyroxine
298 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
298
Total Reports
39
Deaths Reported
1310.0%
Death Rate
Active Ingredients
Thyroxine
Administration Routes
OralUnknown
Species Affected
Dog 295
Cat 2
Human 1
Most Affected Breeds
Retriever - Labrador 45
Retriever - Golden 31
Crossbred Canine/dog 15
Beagle 14
Boxer (German Boxer) 9
Shepherd Dog - German 9
Shih Tzu 8
Collie - Border 8
Siberian Husky 8
Chihuahua 7
Most Reported Reactions
Vomiting 54
Lethargy (see also Central nervous system depression in 'Neurological') 49
Other abnormal test result NOS 39
Diarrhoea 33
Anorexia 28
Elevated alanine aminotransferase (ALT) 27
Death by euthanasia 23
Polydipsia 23
Elevated serum alkaline phosphatase (SAP) 22
Weight loss 20
Seizure NOS 20
Polyuria 20
Outcome Breakdown
Ongoing
122 (40.9%)
Outcome Unknown
71 (23.8%)
Recovered/Normal
65 (21.8%)
Euthanized
23 (7.7%)
Died
16 (5.4%)
Recovered with Sequela
1 (0.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.