Drug profile

The FDA adverse-event record for 30Mg Pyrantel Pamoate/ 30Mg Praziquantel

172 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference 30Mg Pyrantel Pamoate/ 30Mg Praziquantel. See the species affected, top reactions, and outcomes below.

172
adverse-event reports
9.9%
death-coded share
Dog
most-reported species
70
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
172
Total Reports
17
Deaths Reported
9.9%
Death Rate

Active Ingredients

30Mg Pyrantel Pamoate/ 30Mg Praziquantel

Administration Routes

OralUnknown

Species Affected

Dog 170
Cat 1
Unknown 1

Most Affected Breeds

Chihuahua 21
Shih Tzu 19
American Pit Bull Terrier 14
Dog (unknown) 13
Terrier - Yorkshire 10
Spitz - German Pomeranian 8
Shepherd Dog - German 7
Retriever - Labrador 7
Dachshund - Miniature 6
Pinscher - Miniature 6

Most Reported Reactions

Vomiting 70
Lethargy (see also Central nervous system depression in 'Neurological') 55
Diarrhoea 30
Not eating 15
Bloody diarrhoea 11
Death 11
Anorexia 11
Behavioural disorder NOS 8
Distension of abdomen 8
Inappetence 7
Incorrect dose administered NOS 7
Ataxia 6

Outcome Breakdown

Outcome Unknown
88 (51.5%)
Recovered/Normal
64 (37.4%)
Died
12 (7.0%)
Euthanized
5 (2.9%)
Ongoing
2 (1.2%)

30Mg Pyrantel Pamoate/ 30Mg Praziquantel Adverse Event Insights

172 reports name 30Mg Pyrantel Pamoate/ 30Mg Praziquantel; 17 recorded a death outcome (9.9% of reported events, not a population-level mortality rate). Active ingredient: 30Mg Pyrantel Pamoate/ 30Mg Praziquantel. Administration routes: Oral, Unknown.

By species: Dog (170 reports), Cat (1 reports), Unknown (1 reports). By breed: Chihuahua (21), Shih Tzu (19), American Pit Bull Terrier (14).

Leading clinical signs: Vomiting (70), Lethargy (see also Central nervous system depression in 'Neurological') (55), Diarrhoea (30), Not eating (15). Outcome, 171 coded reports: Outcome Unknown leads at 51.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.