Drug profile

The FDA adverse-event record for 30Mg Pyrantel Pamoate/ 30Mg Praziquantel

172 FDA reports name 30Mg Pyrantel Pamoate/ 30Mg Praziquantel, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#572 of 2,679
by report volume (all drugs)
172
adverse-event reports
9.9%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, 30Mg Pyrantel Pamoate/ 30Mg Praziquantel ranks #572 of 2679 by total reports (172) and #552 of 1130 by death-coded share (9.9%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#572
This drug, reports of 2679
#552
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. 30Mg Pyrantel Pamoate/ 30Mg Praziquantel has 172 reports now versus 172 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to 30Mg Pyrantel Pamoate/ 30Mg Praziquantel changes

Signature read: 172 reports place 30Mg Pyrantel Pamoate/ 30Mg Praziquantel in the upper third of FDA AER volume (#572 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
172
Total Reports
17
Deaths Reported
9.9%
Death-coded share of reports

Active Ingredients

30Mg Pyrantel Pamoate/ 30Mg Praziquantel

Administration Routes

OralUnknown

Species Affected

Dog 170
Cat 1
Unknown 1

Most Affected Breeds

Chihuahua 21
Shih Tzu 19
American Pit Bull Terrier 14
Dog (unknown) 13
Terrier - Yorkshire 10
Spitz - German Pomeranian 8
Shepherd Dog - German 7
Retriever - Labrador 7
Dachshund - Miniature 6
Pinscher - Miniature 6

Most Reported Reactions

Vomiting 70
Lethargy (see also Central nervous system depression in 'Neurological') 55
Diarrhoea 30
Not eating 15
Bloody diarrhoea 11
Anorexia 11
Death 11
Behavioural disorder NOS 8
Distension of abdomen 8
Inappetence 7
Incorrect dose administered NOS 7
Ataxia 6

Outcome Breakdown

Outcome Unknown
88 (51.5%)
Recovered/Normal
64 (37.4%)
Died
12 (7.0%)
Euthanized
5 (2.9%)
Ongoing
2 (1.2%)

30Mg Pyrantel Pamoate/ 30Mg Praziquantel: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for 30Mg Pyrantel Pamoate/ 30Mg Praziquantel, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare 30Mg Pyrantel Pamoate/ 30Mg Praziquantel's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for 30Mg Pyrantel Pamoate/ 30Mg Praziquantel (#572 of 2,679 by report volume); death-coded 9.9%. PlainBreed drug row · report volume stamp 172 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →