Drug profile

The FDA adverse-event record for Unspecified Rabies Vaccine

87 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Rabies Vaccine. See the species affected, top reactions, and outcomes below.

87
adverse-event reports
8.0%
death-coded share
Dog
most-reported species
23
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
87
Total Reports
7
Deaths Reported
8.0%
Death Rate

Active Ingredients

Unspecified Rabies Vaccine

Administration Routes

UnknownSubcutaneousIntramuscular

Species Affected

Dog 65
Cat 21
Horse 1

Most Affected Breeds

Domestic Shorthair 16
Retriever - Labrador 7
Chihuahua 4
Terrier - Bull - American Pit 4
Shepherd Dog - German 4
Crossbred Canine/dog 3
Terrier (unspecified) 3
Domestic Mediumhair 2
Schnauzer - Miniature 2
Shepherd Dog - Australian 2

Most Reported Reactions

Vomiting 23
Lethargy (see also Central nervous system depression in Neurological) 18
Diarrhoea 15
Anorexia 14
Lethargy (see also Central nervous system depression in 'Neurological') 8
Emesis (multiple) 6
Not eating 6
Fever 5
Ataxia 5
Decreased appetite 5
Hypersalivation 4
Lack of efficacy (ectoparasite) - flea 4

Outcome Breakdown

Outcome Unknown
32 (36.8%)
Ongoing
30 (34.5%)
Recovered/Normal
18 (20.7%)
Euthanized
4 (4.6%)
Died
3 (3.4%)

Unspecified Rabies Vaccine Adverse Event Insights

87 reports name Unspecified Rabies Vaccine; 7 recorded a death outcome (8.0% of reported events, not a population-level mortality rate). Active ingredient: Unspecified Rabies Vaccine. Administration routes: Unknown, Subcutaneous, Intramuscular.

By species: Dog (65 reports), Cat (21 reports), Horse (1 reports). By breed: Domestic Shorthair (16), Retriever - Labrador (7), Chihuahua (4).

Leading clinical signs: Vomiting (23), Lethargy (see also Central nervous system depression in Neurological) (18), Diarrhoea (15), Anorexia (14). Outcome, 87 coded reports: Outcome Unknown leads at 36.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.