Drug profile

The FDA adverse-event record for Unspecified Rabies Vaccine

89 FDA reports name Unspecified Rabies Vaccine, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#826 of 2,679
by report volume (all drugs)
89
adverse-event reports
7.9%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Unspecified Rabies Vaccine ranks #821 of 2679 by total reports (89) and #649 of 1130 by death-coded share (7.9%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#821
This drug, reports of 2679
#649
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Unspecified Rabies Vaccine has 89 reports now versus 88 in that prior snapshot: 1 more (1.1%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Unspecified Rabies Vaccine changes

Signature read: 89 reports place Unspecified Rabies Vaccine in the upper third of FDA AER volume (#826 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
89
Total Reports
7
Deaths Reported
7.9%
Death-coded share of reports

Active Ingredients

Unspecified Rabies Vaccine

Administration Routes

UnknownSubcutaneousIntramuscularOther

Species Affected

Dog 66
Cat 22
Horse 1

Most Affected Breeds

Domestic Shorthair 17
Retriever - Labrador 7
Chihuahua 4
Shepherd Dog - German 4
Terrier - Bull - American Pit 4
Crossbred Canine/dog 3
Terrier (unspecified) 3
Domestic Mediumhair 2
Schnauzer - Miniature 2
Terrier - Yorkshire 2

Most Reported Reactions

Vomiting 23
Lethargy (see also Central nervous system depression in Neurological) 18
Diarrhoea 15
Anorexia 14
Lethargy (see also Central nervous system depression in 'Neurological') 8
Emesis (multiple) 6
Not eating 6
Decreased appetite 6
Fever 5
Ataxia 5
Hypersalivation 4
Lack of efficacy (ectoparasite) - flea 4

Outcome Breakdown

Outcome Unknown
32 (36.0%)
Ongoing
31 (34.8%)
Recovered/Normal
19 (21.3%)
Euthanized
4 (4.5%)
Died
3 (3.4%)

Unspecified Rabies Vaccine: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Unspecified Rabies Vaccine, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Unspecified Rabies Vaccine's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Unspecified Rabies Vaccine (#826 of 2,679 by report volume); death-coded 7.9%. PlainBreed drug row · report volume stamp 89 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →