Drug profile

The FDA adverse-event record for Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride

66 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride. Species, reactions, and outcomes follow.

#967 of 2,679
by report volume (all drugs)
66
adverse-event reports
13.6%
death-coded share
Cat
most-reported species
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Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride ranks #959 of 2679 by total reports (66) and #410 of 1130 by death-coded share (13.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#959
This drug, reports of 2679
#410
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride has 66 reports now versus 60 in that prior snapshot: 6 more (10.0%).

Report change
+6
Death-coded reports
+2
Death-coded share
+2.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride changes

Signature read: death-coded report count at 9 is the most distinctive stamp on Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
66
Total Reports
9
Deaths Reported
13.6%
Death-coded share of reports

Active Ingredients

Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride

Administration Routes

IntravenousSubcutaneousUnknownParenteral

Species Affected

Cat 35
Dog 31

Most Affected Breeds

Domestic Shorthair 15
Domestic Longhair 6
Domestic Mediumhair 6
Retriever - Labrador 4
Shepherd Dog - German 3
Spitz - German Pomeranian 3
Dachshund (unspecified) 2
Persian 2
Shih Tzu 2
Schnauzer - Miniature 2

Most Reported Reactions

Not eating 10
Behavioural disorder NOS 10
Vomiting 10
Lethargy (see also Central nervous system depression in Neurological) 10
Other abnormal test result NOS 9
Anorexia 8
Weight loss 8
Decreased appetite 6
Death 6
Lack of efficacy - NOS 5
Seizure NOS 5
Elevated blood urea nitrogen (BUN) 5

Outcome Breakdown

Recovered/Normal
20 (30.3%)
Ongoing
20 (30.3%)
Outcome Unknown
16 (24.2%)
Died
6 (9.1%)
Euthanized
3 (4.5%)
Recovered with Sequela
1 (1.5%)

Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (13.6% here), distinct from the volume row.

Canine Bb/Pi3/Adeno 2 Lv/Lb 13.6% Cimetidine 13.7% Unspecified Medications 13.7% Zeranol 13.7%

What to do with this drug

  • Compare Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride (#967 of 2,679 by report volume); death-coded 13.6%. PlainBreed drug row · death-coded report count stamp 9 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →