Drug profile

The FDA adverse-event record for Crystalloid Fluids

60 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Crystalloid Fluids. See the species affected, top reactions, and outcomes below.

60
adverse-event reports
35.0%
death-coded share
Dog
most-reported species
14
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
60
Total Reports
21
Deaths Reported
35.0%
Death Rate

Active Ingredients

Crystalloid Fluids

Administration Routes

UnknownIntravenousSubcutaneous

Species Affected

Dog 32
Cat 27
Cattle 1

Most Affected Breeds

Domestic Shorthair 15
Retriever - Labrador 4
Retriever - Golden 4
Domestic Longhair 3
Domestic Mediumhair 3
Beagle 2
Dog (unknown) 2
Spaniel - Springer English 2
Persian 2
Doberman Pinscher 2

Most Reported Reactions

Vomiting 14
Other abnormal test result NOS 12
Weight loss 12
Not eating 11
Dehydration 9
Death by euthanasia 9
Behavioural disorder NOS 9
Hyperglycaemia 9
Death 9
Lethargy (see also Central nervous system depression in Neurological) 9
Anorexia 8
Abnormal ultrasound finding 7

Outcome Breakdown

Outcome Unknown
15 (24.6%)
Ongoing
14 (23.0%)
Died
12 (19.7%)
Recovered/Normal
11 (18.0%)
Euthanized
9 (14.8%)

Crystalloid Fluids Adverse Event Insights

60 reports name Crystalloid Fluids; 21 recorded a death outcome (35.0% of reported events, not a population-level mortality rate). Active ingredient: Crystalloid Fluids. Administration routes: Unknown, Intravenous, Subcutaneous.

By species: Dog (32 reports), Cat (27 reports), Cattle (1 reports). By breed: Domestic Shorthair (15), Retriever - Labrador (4), Retriever - Golden (4).

Leading clinical signs: Vomiting (14), Other abnormal test result NOS (12), Weight loss (12), Not eating (11). Outcome, 61 coded reports: Outcome Unknown leads at 24.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.