Drug profile

The FDA adverse-event record for Soap

57 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Soap. See the species affected, top reactions, and outcomes below.

57
adverse-event reports
3.5%
death-coded share
Dog
most-reported species
18
Lack of efficacy (ectoparasite) - flea - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
57
Total Reports
2
Deaths Reported
3.5%
Death Rate

Active Ingredients

Soap

Administration Routes

TopicalUnknownOther

Species Affected

Dog 26
Human 18
Cat 13

Most Affected Breeds

Unknown 18
Domestic Shorthair 9
Chihuahua 4
Spitz - German Pomeranian 3
Boxer (German Boxer) 2
Shepherd Dog - Australian 2
Mixed (Dog) 1
Terrier - West Highland White 1
Himalayan 1
Dachshund (unspecified) 1

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 18
Accidental exposure 11
Lethargy (see also Central nervous system depression in 'Neurological') 6
Weight loss 5
Diarrhoea 5
Vomiting 5
Application site scab 4
Pruritus 4
Application site erythema 3
Application site pruritus 3
Falling 3
Behavioural disorder NOS 3

Outcome Breakdown

Outcome Unknown
31 (54.4%)
Recovered/Normal
12 (21.1%)
Ongoing
12 (21.1%)
Died
2 (3.5%)

Soap Adverse Event Insights

57 reports name Soap; 2 recorded a death outcome (3.5% of reported events, not a population-level mortality rate). Active ingredient: Soap. Administration routes: Topical, Unknown, Other.

By species: Dog (26 reports), Human (18 reports), Cat (13 reports). By breed: Unknown (18), Domestic Shorthair (9), Chihuahua (4).

Leading clinical signs: Lack of efficacy (ectoparasite) - flea (18), Accidental exposure (11), Lethargy (see also Central nervous system depression in 'Neurological') (6), Weight loss (5). Outcome, 57 coded reports: Outcome Unknown leads at 54.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.