Cyclophosphamide
53 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
53
Total Reports
15
Deaths Reported
2830.0%
Death Rate
Active Ingredients
Cyclophosphamide
Administration Routes
UnknownOralIntravenous
Species Affected
Dog 43
Cat 10
Most Affected Breeds
Domestic Shorthair 6
Retriever - Labrador 6
Retriever - Golden 5
Beagle 3
Pit Bull 3
Cat (unknown) 2
Rottweiler 2
Terrier - Bull - American Pit 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Boxer (German Boxer) 2
Most Reported Reactions
Death by euthanasia 13
Vomiting 9
Lack of efficacy - NOS 7
Lethargy (see also Central nervous system depression in 'Neurological') 6
Fever 6
Weight loss 6
Diarrhoea 6
Anorexia 5
Decreased appetite 5
Elevated alanine aminotransferase (ALT) 5
Anaemia NOS 4
Elevated serum alkaline phosphatase (SAP) 4
Outcome Breakdown
Ongoing
20 (37.7%)
Euthanized
13 (24.5%)
Outcome Unknown
9 (17.0%)
Recovered/Normal
9 (17.0%)
Died
2 (3.8%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.