Ivermectin + Praziquantel

460 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

460

Total Reports

Deaths Reported

370.0%

Death Rate

Active Ingredients

IvermectinIvermectin + PraziquantelPraziquantel

Administration Routes

OralUnknown

Species Affected

Horse 365

Unknown 66

Dog 19

Donkey 5

Human 2

Cat 1

Rabbit 1

Llama 1

Most Affected Breeds

Quarter Horse 89

Unknown 72

Horse (unknown) 60

Thoroughbred 40

Horse (other) 40

Arab 18

Paint 17

Crossbred Equine/horse 14

Tennessee Walking Horse 13

Warmblood (unspecified) 8

Most Reported Reactions

Swollen mouth 73

Application site swelling 58

Oral swelling 55

Hypersalivation 53

Swollen lip (see also 'Skin') 45

Swollen tongue 44

Anorexia 33

Tongue protrusion 22

Drooling 21

Locking Mechanism Abnormal 19

Colic 18

Application site inflammation 17

Outcome Breakdown

Recovered/Normal

224 (55.7%)

Outcome Unknown

131 (32.6%)

Ongoing

29 (7.2%)

Died

12 (3.0%)

Euthanized

5 (1.2%)

Recovered with Sequela

1 (0.2%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.