Sirolimus

10 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

6000.0%

Death Rate

Active Ingredients

Sirolimus

Administration Routes

OralUnknown

Species Affected

Cat 9

Dog 1

Most Affected Breeds

Domestic Shorthair 4

Shepherd Dog - German 1

American Shorthair 1

Domestic Longhair 1

Cat (unknown) 1

Cat (other) 1

Sphynx 1

Most Reported Reactions

Death 3

Vomiting 2

Hypokalaemia 2

Congestive heart failure 2

Bloody diarrhoea 1

Overdose 1

Lethargy (see also Central nervous system depression in Neurological) 1

Renal disorder NOS 1

Elevated lactate 1

Elevated aspartate aminotransferase (AST) 1

Elevated alanine aminotransferase (ALT) 1

Discomfort NOS 1

Outcome Breakdown

Euthanized

3 (30.0%)

Died

3 (30.0%)

Recovered/Normal

2 (20.0%)

Ongoing

2 (20.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.