Drug profile

The FDA adverse-event record for Prescription Diet (Unspecified)

361 FDA reports name Prescription Diet (Unspecified), a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#373 of 2,679
by report volume (all drugs)
361
adverse-event reports
15.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Prescription Diet (Unspecified) ranks #373 of 2679 by total reports (361) and #350 of 1130 by death-coded share (15.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#373
This drug, reports of 2679
#350
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Prescription Diet (Unspecified) has 361 reports now versus 361 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Prescription Diet (Unspecified) changes

Signature read: death-coded report count at 56 is the most distinctive stamp on Prescription Diet (Unspecified)'s FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
361
Total Reports
56
Deaths Reported
15.5%
Death-coded share of reports

Active Ingredients

Prescription Diet (Unspecified)

Administration Routes

OralUnknown

Species Affected

Dog 262
Cat 99

Most Affected Breeds

Domestic Shorthair 68
Retriever - Labrador 31
Shih Tzu 20
Terrier - Yorkshire 19
Retriever - Golden 13
Shepherd Dog - German 12
Bichon Frise 8
Chihuahua 8
Corgi (unspecified) 7
Terrier - Bull - American Pit 7

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 87
Vomiting 73
Anorexia 68
Diarrhoea 55
Other abnormal test result NOS 47
Weight loss 44
Death by euthanasia 36
Behavioural disorder NOS 28
Emesis 26
Lack of efficacy - NOS 25
INEFFECTIVE, LOSS OF EFFECT 25
Decreased appetite 22

Outcome Breakdown

Ongoing
184 (51.0%)
Outcome Unknown
61 (16.9%)
Recovered/Normal
60 (16.6%)
Euthanized
36 (10.0%)
Died
20 (5.5%)

Prescription Diet (Unspecified): high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Prescription Diet (Unspecified), both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (361 here).

Similar death-coded share

Nearest other drugs by death-coded share (15.5% here), distinct from the volume row.

What to do with this drug

  • Compare Prescription Diet (Unspecified)'s report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Prescription Diet (Unspecified) (#373 of 2,679 by report volume); death-coded 15.5%. PlainBreed drug row · death-coded report count stamp 56 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →