Misoprostol

141 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

141

Total Reports

Deaths Reported

1630.0%

Death Rate

Active Ingredients

Misoprostol

Administration Routes

UnknownOral

Species Affected

Horse 77

Dog 61

Cat 2

Donkey 1

Most Affected Breeds

Retriever - Labrador 18

Warmblood (unspecified) 17

Quarter Horse 13

Horse (unknown) 12

Thoroughbred 7

Arab 4

Paint 4

Shepherd (unspecified) 3

Siberian Husky 3

Mixed (Dog) 2

Most Reported Reactions

Lack of efficacy - NOS 56

Vomiting 25

INEFFECTIVE, GASTRIC ULCER(S) 23

Lethargy (see also Central nervous system depression in 'Neurological') 20

Death by euthanasia 19

Anorexia 17

Elevated alanine aminotransferase (ALT) 17

Elevated serum alkaline phosphatase (SAP) 16

Diarrhoea 16

Anaemia NOS 15

Other abnormal test result NOS 15

Hypoproteinaemia 12

Outcome Breakdown

Outcome Unknown

54 (38.3%)

Ongoing

43 (30.5%)

Recovered/Normal

20 (14.2%)

Euthanized

19 (13.5%)

Died

4 (2.8%)

Recovered with Sequela

1 (0.7%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.