Drug profile

The FDA adverse-event record for Bacitracin + Neomycin + Polymyxin B

52 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bacitracin + Neomycin + Polymyxin B. Species, reactions, and outcomes follow.

#1088 of 2,679
by report volume (all drugs)
52
adverse-event reports
15.4%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Bacitracin + Neomycin + Polymyxin B ranks #1088 of 2679 by total reports (52) and #351 of 1130 by death-coded share (15.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1088
This drug, reports of 2679
#351
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bacitracin + Neomycin + Polymyxin B has 52 reports now versus 48 in that prior snapshot: 4 more (8.3%).

Report change
+4
Death-coded reports
+1
Death-coded share
+0.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bacitracin + Neomycin + Polymyxin B changes

Signature read: death-coded share at 15.4% is the most distinctive stamp on Bacitracin + Neomycin + Polymyxin B's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
52
Total Reports
8
Deaths Reported
15.4%
Death-coded share of reports

Active Ingredients

BacitracinBacitracin + Neomycin + Polymyxin BNeomycinPolymyxin B

Administration Routes

UnknownOphthalmicTopicalIntraocular

Species Affected

Dog 39
Cat 12
Horse 1

Most Affected Breeds

Domestic Shorthair 10
Retriever - Labrador 7
Crossbred Canine/dog 5
Pug 5
Dog (unknown) 4
Dachshund (unspecified) 3
Retriever - Golden 2
Maltese 2
Russian 1
Horse (unknown) 1

Most Reported Reactions

Corneal ulcer 14
Vomiting 11
Diarrhoea 11
Eye disorder NOS (for Photophobia see neurological) 11
Lethargy (see also Central nervous system depression in Neurological) 10
Other abnormal test result NOS 9
Ocular discharge 8
Ataxia 7
Elevated alanine aminotransferase (ALT) 7
Behavioural disorder NOS 7
Neurogenic keratoconjunctivitis sicca (KCS) 7
Cloudy eye (for Miosis, Mydriasis, Anisocoria, Nystagmus - see Neurological) 7

Outcome Breakdown

Ongoing
27 (51.9%)
Outcome Unknown
14 (26.9%)
Euthanized
5 (9.6%)
Recovered/Normal
3 (5.8%)
Died
3 (5.8%)

Bacitracin + Neomycin + Polymyxin B Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Bacitracin + Neomycin + Polymyxin B, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (52 here).

Similar death-coded share

Nearest other drugs by death-coded share (15.4% here), distinct from the volume row.

What to do with this drug

  • Compare Bacitracin + Neomycin + Polymyxin B's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bacitracin + Neomycin + Polymyxin B (#1088 of 2,679 by report volume); death-coded 15.4%. PlainBreed drug row · death-coded share stamp 15.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →