Drug profile

The FDA adverse-event record for Dolasetron

63 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dolasetron. See the species affected, top reactions, and outcomes below.

63
adverse-event reports
49.2%
death-coded share
Dog
most-reported species
29
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
63
Total Reports
31
Deaths Reported
49.2%
Death Rate

Active Ingredients

Dolasetron

Administration Routes

UnknownSubcutaneousOralParenteralIntravenous

Species Affected

Dog 54
Cat 9

Most Affected Breeds

Retriever - Labrador 14
Domestic Shorthair 5
Beagle 4
Spaniel (unspecified) 3
Spitz - German Pomeranian 3
Maltese 2
Terrier - Bull - American Pit 2
Retriever - Golden 2
Bichon Frise 2
Chihuahua 2

Most Reported Reactions

Vomiting 29
Other abnormal test result NOS 24
Lethargy (see also Central nervous system depression in 'Neurological') 22
Death by euthanasia 21
Elevated serum alkaline phosphatase (SAP) 21
Elevated alanine aminotransferase (ALT) 20
Anorexia 19
Abnormal ultrasound finding 18
Diarrhoea 18
Elevated total bilirubin 17
Anaemia NOS 16
Leucocytosis NOS 14

Outcome Breakdown

Ongoing
22 (34.4%)
Euthanized
20 (31.3%)
Died
11 (17.2%)
Recovered/Normal
8 (12.5%)
Outcome Unknown
3 (4.7%)

Dolasetron Adverse Event Insights

63 reports name Dolasetron; 31 recorded a death outcome (49.2% of reported events, not a population-level mortality rate). Active ingredient: Dolasetron. Administration routes: Unknown, Subcutaneous, Oral, Parenteral.

By species: Dog (54 reports), Cat (9 reports). By breed: Retriever - Labrador (14), Domestic Shorthair (5), Beagle (4).

Leading clinical signs: Vomiting (29), Other abnormal test result NOS (24), Lethargy (see also Central nervous system depression in 'Neurological') (22), Death by euthanasia (21). Outcome, 64 coded reports: Ongoing leads at 34.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.