Atipamezole Hydrochloride

1,561 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,561
Total Reports
266
Deaths Reported
1700.0%
Death Rate

Active Ingredients

Atipamezole Hydrochloride

Administration Routes

IntramuscularUnknownIntravenousSubcutaneousParenteralOtherIntraperitonealOphthalmicOral

Species Affected

Dog 980
Cat 439
Unknown 111
Rabbit 4
Human 4
Other Rodents 3
Tiger 2
Mouse 2
Chinchilla 2
Rat 2

Most Affected Breeds

Domestic Shorthair 242
Unknown 133
Retriever - Labrador 119
Dog (unknown) 85
Terrier - Bull - American Pit 60
Domestic Longhair 52
Shepherd Dog - German 45
Cat (other) 37
Cat (unknown) 31
Retriever - Golden 30

Most Reported Reactions

Death 189
INEFFECTIVE, REVERSAL 182
Bradycardia 168
Lack of efficacy - NOS 154
Vomiting 139
Lethargy (see also Central nervous system depression in 'Neurological') 124
Sedation prolonged 121
Hypersalivation 116
Cardiac arrest 103
Panting 96
Diarrhoea 94
Seizure NOS 87

Outcome Breakdown

Ongoing
577 (39.4%)
Recovered/Normal
478 (32.6%)
Died
206 (14.1%)
Outcome Unknown
140 (9.6%)
Euthanized
62 (4.2%)
Recovered with Sequela
2 (0.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.