Drug profile

The FDA adverse-event record for Pain Relief Medication Unknown

106 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Pain Relief Medication Unknown. See the species affected, top reactions, and outcomes below.

106
adverse-event reports
35.8%
death-coded share
Dog
most-reported species
39
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
106
Total Reports
38
Deaths Reported
35.8%
Death Rate

Active Ingredients

Pain Relief Medication Unknown

Administration Routes

UnknownOralTopicalOphthalmic

Species Affected

Dog 69
Cat 37

Most Affected Breeds

Domestic Shorthair 16
Retriever - Labrador 9
Domestic Longhair 7
Shih Tzu 4
Cat (other) 4
Chihuahua 3
Terrier - Bull - American Pit 3
Maltese 2
Terrier - Yorkshire 2
Terrier - Boston 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 39
Death 22
Anorexia 22
Vomiting 21
Death by euthanasia 15
Fever 14
Diarrhoea 13
Weight loss 11
Adipsia 11
Leucocytosis NOS 10
Anaemia NOS 10
Not eating 8

Outcome Breakdown

Ongoing
36 (34.0%)
Died
24 (22.6%)
Outcome Unknown
24 (22.6%)
Euthanized
14 (13.2%)
Recovered/Normal
8 (7.5%)

Pain Relief Medication Unknown Adverse Event Insights

106 reports name Pain Relief Medication Unknown; 38 recorded a death outcome (35.8% of reported events, not a population-level mortality rate). Active ingredient: Pain Relief Medication Unknown. Administration routes: Unknown, Oral, Topical, Ophthalmic.

By species: Dog (69 reports), Cat (37 reports). By breed: Domestic Shorthair (16), Retriever - Labrador (9), Domestic Longhair (7).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (39), Death (22), Anorexia (22), Vomiting (21). Outcome, 106 coded reports: Ongoing leads at 34.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.