Drug profile

The FDA adverse-event record for Benazepril Hydrochloride

107 FDA reports name Benazepril Hydrochloride, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#755 of 2,679
by report volume (all drugs)
107
adverse-event reports
21.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Benazepril Hydrochloride ranks #755 of 2679 by total reports (107) and #215 of 1130 by death-coded share (21.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#755
This drug, reports of 2679
#215
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Benazepril Hydrochloride has 107 reports now versus 106 in that prior snapshot: 1 more (0.9%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Benazepril Hydrochloride changes

Signature read: death-coded report count at 23 is the most distinctive stamp on Benazepril Hydrochloride's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
107
Total Reports
23
Deaths Reported
21.5%
Death-coded share of reports

Active Ingredients

Benazepril Hydrochloride

Administration Routes

UnknownOral

Species Affected

Dog 97
Cat 10

Most Affected Breeds

Retriever - Labrador 8
Shih Tzu 7
Retriever - Golden 7
Terrier - Yorkshire 7
Maltese 6
Chihuahua 5
Terrier (unspecified) 4
Mixed (Dog) 4
Domestic Shorthair 4
Dog (unknown) 4

Most Reported Reactions

Vomiting 20
Anorexia 17
Lethargy (see also Central nervous system depression in 'Neurological') 17
Lack of efficacy - NOS 14
Other abnormal test result NOS 14
Diarrhoea 14
Death by euthanasia 13
Elevated blood urea nitrogen (BUN) 12
Elevated serum alkaline phosphatase (SAP) 12
Abnormal ultrasound finding 11
Decreased appetite 10
Elevated creatinine 10

Outcome Breakdown

Ongoing
53 (49.1%)
Outcome Unknown
17 (15.7%)
Recovered/Normal
14 (13.0%)
Euthanized
12 (11.1%)
Died
11 (10.2%)
Recovered with Sequela
1 (0.9%)

Benazepril Hydrochloride: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Benazepril Hydrochloride, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (107 here).

Similar death-coded share

Nearest other drugs by death-coded share (21.5% here), distinct from the volume row.

What to do with this drug

  • Compare Benazepril Hydrochloride's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Benazepril Hydrochloride (#755 of 2,679 by report volume); death-coded 21.5%. PlainBreed drug row · death-coded report count stamp 23 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →