Drug profile

The FDA adverse-event record for Lactated Ringers Solution

107 FDA reports name Lactated Ringers Solution, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#757 of 2,679
by report volume (all drugs)
107
adverse-event reports
35.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Lactated Ringers Solution ranks #755 of 2679 by total reports (107) and #101 of 1130 by death-coded share (35.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#755
This drug, reports of 2679
#101
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lactated Ringers Solution has 107 reports now versus 104 in that prior snapshot: 3 more (2.9%).

Report change
+3
Death-coded reports
+2
Death-coded share
+0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lactated Ringers Solution changes

Signature read: Lactated Ringers Solution's 35.5% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
107
Total Reports
38
Deaths Reported
35.5%
Death-coded share of reports

Active Ingredients

Lactated Ringers Solution

Administration Routes

IntravenousSubcutaneousUnknown

Species Affected

Dog 59
Cat 41
Horse 6
Guinea Pig 1

Most Affected Breeds

Domestic Shorthair 27
Terrier - Bull - American Pit 6
Terrier - Yorkshire 4
Domestic Longhair 3
Pit Bull 3
Chihuahua 3
Retriever - Labrador 3
Cat (other) 3
Alaskan Malamute 3
Quarter Horse 3

Most Reported Reactions

Anorexia 25
Vomiting 24
Death by euthanasia 20
Other abnormal test result NOS 18
Death 18
Lethargy (see also Central nervous system depression in Neurological) 17
Weight loss 16
Tachycardia 16
Dehydration 15
Diarrhoea 15
Ataxia 14
Lethargy (see also Central nervous system depression in 'Neurological') 13

Outcome Breakdown

Outcome Unknown
27 (25.2%)
Recovered/Normal
23 (21.5%)
Euthanized
20 (18.7%)
Died
18 (16.8%)
Ongoing
17 (15.9%)
Recovered with Sequela
2 (1.9%)

Lactated Ringers Solution: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Lactated Ringers Solution, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (107 here).

Similar death-coded share

Nearest other drugs by death-coded share (35.5% here), distinct from the volume row.

What to do with this drug

  • Compare Lactated Ringers Solution's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lactated Ringers Solution (#757 of 2,679 by report volume); death-coded 35.5%. PlainBreed drug row · death-coded share stamp 35.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →