Drug profile

The FDA adverse-event record for Oxygen

260 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Oxygen. See the species affected, top reactions, and outcomes below.

260
adverse-event reports
37.3%
death-coded share
Dog
most-reported species
54
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
260
Total Reports
97
Deaths Reported
37.3%
Death Rate

Active Ingredients

Oxygen

Administration Routes

Respiratory (Inhalation)UnknownNasalOtherIntravenousEndotracheal

Species Affected

Dog 161
Cat 93
Rabbit 2
Other Birds 1
Other Amphibians 1
Guinea Pig 1
Mouse 1

Most Affected Breeds

Domestic Shorthair 66
Retriever - Labrador 16
Pug 9
Terrier (unspecified) 9
Crossbred Canine/dog 8
Chihuahua 7
Bulldog - French 7
Dog (unknown) 6
Bengal 5
Terrier - Boston 5

Most Reported Reactions

Death 54
Vomiting 44
Death by euthanasia 41
Lethargy (see also Central nervous system depression in Neurological) 34
Tachycardia 30
Anaphylaxis 28
Other abnormal test result NOS 27
Cardiac arrest 25
Anorexia 24
Abnormal radiograph finding 24
Elevated alanine aminotransferase (ALT) 24
Pale mucous membrane 23

Outcome Breakdown

Recovered/Normal
71 (27.0%)
Died
56 (21.3%)
Ongoing
49 (18.6%)
Outcome Unknown
44 (16.7%)
Euthanized
41 (15.6%)
Recovered with Sequela
2 (0.8%)

Oxygen Adverse Event Insights

260 reports name Oxygen; 97 recorded a death outcome (37.3% of reported events, not a population-level mortality rate). Active ingredient: Oxygen. Administration routes: Respiratory (Inhalation), Unknown, Nasal, Other.

By species: Dog (161 reports), Cat (93 reports), Rabbit (2 reports). By breed: Domestic Shorthair (66), Retriever - Labrador (16), Pug (9).

Leading clinical signs: Death (54), Vomiting (44), Death by euthanasia (41), Lethargy (see also Central nervous system depression in Neurological) (34). Outcome, 263 coded reports: Recovered/Normal leads at 27.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.